Everton vs. Liverpool Prediction, Picks, XIs for Premier League – Sunday, 4/19

Hill Dickinson Stadium is set to host its first-ever Merseyside Derby on Sunday, April 19, when Everton hosts Liverpool in a Premier League match at 9 a.m. ET on USA Network.

Liverpool are slightly favored to defeat Everton on the road, returning a 2.22x payout if they claim victory, according to PrizePicks Team Picks.

A win for Everton would pull them within two points of Liverpool, who enter the weekend in the final Champions League spot for next season.

Liverpool will need to snap a four-match away losing skid in all competitions if they’re to maintain their grip on fifth place.

Below, we’ll break down our Everton vs. Liverpool prediction and picks for Sunday morning’s Premier League match, including the spread, total goals, and key player picks for PrizePicks.

‍Make your picks for Everton vs. Liverpool on PrizePicks now. 

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Everton vs. Liverpool Prediction, Spread, Total Goals for Premier League – Sunday, April 19

Everton will look to start their Merseyside Derby history at their new ground in similar fashion to how they closed at Goodison Park. The Toffees got a 98th-minute piledriver goal from James Tarkowski on Feb. 12, 2025, to secure a 2-2 draw and go three unbeaten at home vs. Liverpool.

That’s been a familiar result in this fixture. Dating back to 2012, the last 13 Merseyside Derbies hosted by Everton have featured 10 draws, with Liverpool winning on two occasions. In comparison, Liverpool have won 13 of the 17 meetings at Anfield in all competitions during that same span.

If Liverpool are to break through, they will do so without ST Hugo Ekitike. The French forward tore his Achilles tendon in Liverpool’s 2-0 defeat at PSG on Tuesday, and he will miss the rest of the season and the World Cup.

They also remain without GK Alisson, CB Joe Gomez, RB Conor Bradley, and MF Wataru Endo. ST Alexander Isak is still not back to full-match fitness but will likely start and play at least 60 minutes.

The home side will still be without MF Jack Grealish, but Everton are otherwise healthy. They’re in solid form, with only Everton denying them points in their last five matches.

The Toffees have conceded just one goal in their last three home matches, but have actually performed much better on the road this campaign. However, Liverpool have just one win in their last five in all competitions.

Perhaps the most damning stat for Liverpool is how they’ve performed on the road vs. quality opponents. In six away fixtures this season against teams currently in the top half of the table, Liverpool have claimed just one point. 

One player to keep an eye on is RW Mohamed Salah. The Liverpool legend is playing his final Merseyside Derby, and has scored in four of his last six starts for the Reds despite a rough campaign. This could be a spot where Salah adds one final chapter to his time at the club.

Everton vs. Liverpool Spread, Total Goals, Match Payouts – Sunday, April 19

Liverpool enters Sunday’s Premier League match as road favorites, returning a 2.22x payout if they win outright, via PrizePicks Team Picks.

Here are the full payouts for the Everton vs. Liverpool match on PrizePicks.

‍Winner Payout: Everton – 2.94x | Tie – 3.12x | Liverpool – 2.22x

Spread: Liverpool -1.5 (4.34x Payout) 

Total Goals: 2.5 (Over – 1.85x)

Both Teams to Score (BTTS): Yes 1.63x | No 2.12x

‍Play the Everton vs. Liverpool spread or total goals on PrizePicks Team Picks to earn real money— available in 35 states!

‍Team Picks data is live at the time of writing and is subject to change.

Everton vs. Liverpool Prediction on Total Goals – Sunday, April 19

Here are the key stats and trends behind our Everton vs. Liverpool prediction on total goals for Sunday, April 19.

Lock in your Everton vs. Liverpool prediction on PrizePicks before the line moves.

  • Liverpool opponents take more than 36% of their shots from outside the box, the third-highest mark in the Premier League.
  • The 8% of shots taken against Liverpool inside the six-yard area are the lowest against any side in the league.
  • Everton allow just 0.08 goals per shot, the third-fewest in the Premier League.
  • Everton also ranks fourth in goals per shot on target, with a 0.25 G/SOT mark.
  • Liverpool have been the least accurate side in the Premier League, putting just 28.8% of their shots on target. 
  • Everton’s 11 clean sheets this season are the fourth-most of any Premier League side.

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Everton vs. Liverpool Projected Lineups for Sunday, April 19

Here are the projected Everton vs. Liverpool lineups for today’s Premier League match on Sunday, April 19. Lineups are not official.

Everton Lineup vs. Liverpool: Projected 4-2-3-1

  • Goalkeeper: Jordan Pickford
  • Defense: Jake O’Brien, James Tarkowski, Jarrad Branthwaite, Vitaliy Mykolenko
  • Midfield: James Garner, Idrissa Gana Gueye, Kiernan Dewsbury-Hall
  • Forwards: Dwight McNeil, Beto, Iliman Ndiaye

Liverpool Lineup vs. Everton: Projected 4-2-3-1

  • Goalkeeper: Giorgi Mamardashvili
  • Defense: Jeremie Frimpong, Ibrahima Konate, Virgil van Dijk, Milos Kerkez
  • Midfield: Ryan Gravenberch, Alexis Mac Allister, Dominik Szoboszlai
  • Forwards: Mohamed Salah, Alexander Isak, Florian Wirtz

Everton vs. Liverpool Picks, Match Stats for PrizePicks: 4/19/26

Here are two Everton vs. Liverpool picks for the Merseyside derby match on PrizePicks, for Sunday, April 19. Today’s Premier League picks for PrizePicks are headlined by Mohamed Salah and James Tarkowski.

Liverpool FW Mohamed Salah vs. Everton: 2.5 Attempted Dribbles 

  • Salah has attempted at least 3 dribbles in each of his last four matches.
  • Salah averaged 3.33 dribbles per match in his last three meetings with Everton.
  • Liverpool operates 37% of their attacking action down their right flank away from Anfield, the sixth-highest rate of any team in the Premier League.
  • Everton ranks fourth in possession kept per match, while Liverpool’s 59.9% possession ranks second in the league.

Add Mohamed Salah to your PrizePicks Lineup now.

Everton CB James Tarkowski vs. Liverpool: 6.5 Clearances

  • James Tarkowski ranks third in the Premier League this season with 215 clearances, per Opta.
  • The Everton defender has at least 8 clearances in each of his last four Merseyside Derbies, registering 37 in total.
  • Everton have performed 974 clearances this season, fifth-most of any side.
  • Liverpool’s 1107 touches in their opponent’s penalty box are the most of any club in the Premier League.

Add James Tarkowski to your PrizePicks Lineup now. 

Make Your Everton vs. Liverpool Prediction on PrizePicks

Sunday’s Merseyside Derby carries high stakes for both Everton and Liverpool. The Reds will be desperate to hang onto Champions League football for next season, while Everton will hope of reaching Europe’s top competition by pulling off the upset of their hated rivals.

Don’t wait until lock — make your Everton vs. Liverpool picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 35 states.

Stay locked in on Playbook for more Premier League predictions and expert picks through the end of the season.

Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

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