China approves first domestically made mRNA vaccine for Covid


China has approved its first domestically produced messenger RNA (mRNA) Covid-19 jab, a vaccine that its developer said worked well against some recent variants, including the dominant strain in the United States.

The National Medical Products Administration (NMPA) approved the SYS6006 vaccine, developed by CSPC Pharmaceutical, for emergency use on Wednesday about a year after its clinical trials began, according to the company.

The new jab would be the first of its kind to be rolled out in the mainland market. China has not authorised any foreign-produced mRNA vaccines for its citizens.

The Hebei-based company said it tested the jabs on about 4,000 cases in a study from December 10 to January 18, and found the booster efficacy to be more than 85 per cent after two to four weeks.

The data has not been published in a peer-reviewed journal.

“Clinical study shows that SYS6006, either as a basic shot or booster shot, could consistently enhance the reactivity of T cells to various variants including Delta, Omicron BA.2 and BA.5 in a high and more enduring manner,” the statement said.

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T cells are immune cells that coordinate immune responses and kill cells that are infected with viruses.

The jab also demonstrated a neutralising effect “very well” on highly transmissible Omicron strains like BF.7, BQ.1.1, and XBB.1.5 – the lineage that accounted for more than 90 per cent of variants circulating in the US – and CH.1.1, the company said.

While BA.5.2 and BF.7 comprise most cases in China, local or imported cases of BQ.1.1, XBB.1.5, and CH.1.1 were identified, according to the latest national data.

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The shot also carries milder side effects – like fever and injection site soreness – with “significantly lower” frequency and severity of side effects in the elderly, according to the company.

mRNA vaccines – widely used in the rest of the world – use messenger RNA molecules to teach the body to generate specialised proteins and activate T cells to trigger an immune response.

The traditional vaccines that China has been deploying use inactivated, adenovirus-vectored or protein recombination technology.

The approval in China came after an annual political meeting known as the “ two sessions”, during which “more scientific, accurate, and effective prevention” of Covid-19 was an agenda item in the government work report.
In the first press conference held by the new State Council, China’s cabinet, Premier Li Qiang signalled the need to “speed up the development of new vaccines and drugs”.

Video: China’s Li Qiang shakes off Shanghai Covid chaos to become new premier

China saw one of the world’s biggest waves of Covid-19 this past winter after it suddenly dropped its stringent Covid restrictions. Although infection numbers began to level off about a month later, experts expected smaller and successive waves to follow over the next few months, and stressed that approvals for more effective vaccines should be sped up.

At least five other Chinese drug makers have said they are developing mRNA vaccines. Walvax and AIM Vaccine said they were conducting or had completed clinical trials, but development and administrative processes had been slow.

AWcorna, co-developed by Yuxi Walvax with Suzhou Abogen Biosciences and the Academy of Military Sciences, was authorised for emergency use in Indonesia in September last year but has not yet been approved for China.



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彭博社報道,Nationwide首席策略師Mark Hackett表示,「隨著貿易緊張局勢緩和,投資者正重新聚焦基本面,但他們可能不會喜歡他們所看到的」,「市場在極短時間內從超賣迅速轉向超買。這將限制短期內上漲空間,除非我們看到經濟成長明顯加速」。 恒指今早高開3點,高位升70點,低位跌144點,高低波幅214點。上升股份比例為20.49%,下跌為33.48%,無升跌為46.01%。 恒指半日跌59點或0.25%,報23581點,大市成交金額1101億元;國指跌22點或0.26%,報8570點。恒生科技指數收報5348點,跌0.62%。 藍籌股成交金額478.57億元,佔大市成交43.46%;科指成份股成交金額299.47億元,佔大市成交27.19%;國指成份股成交金額427.1億元,佔大市成交38.79%。 24隻雙櫃台股,總成交0.47億元人民幣,相當於約0.51億港元,佔大市成交的0.05%。 窩輪及牛熊證成交金額減少28.33%,至130.74億元,佔大市成交11.86%。牛熊證成交金額52.37億元,減少46.23%;窩輪成交金額78.36億元,減少7.82%。 藍籌25隻升,56隻下跌,2隻無升跌。比亞迪(1211)升3.52%,收報429.2元,是升幅最大的藍籌,平保(2318)跌4.85%,收報47.1元,是跌幅最大的藍籌。 恒生科技指數成份股11隻升,18隻下跌,1隻無升跌。升幅最大的是騰訊音樂-SW(1698)創上市新高,見67.65元,收報66.95元,升8.86%;跌幅最大的是京東(9618)收報136.5元,跌3.6%。 恒指10天線(22950.2點)升穿50天線(22790.35點)。科指跌穿50天線(5367.75點)。 北水南下合計淨流入13.36億元,較上日減少80.08%,連續第3日流入,累計流入103.04億元,對上一次連續3日淨流入是4月15日。北水本月累計流出9.55億元。北水交易成交額(包括買入及賣出交易)432.96億元,較上日減57.14%,佔香港市場成交額由上日的22.66%減至19.65%。 大摩上調泡泡瑪特(9992)目標價 曾升逾3%創上市新高。創上市新高,見200.8元,收報199元,升2.74%。 匯控(0005)計劃裁減法國約10%員工。收報90.15元,跌0.72%。 花旗上調騰訊(0700)目標價 維持「買入」評級。騰訊首季多賺22%勝預期,指AI已對廣告及遊戲業務有實質貢獻。收報518.5元,跌0.48%。 中國4月新增貸款規模重挫逾六成。內銀股 建行(0939)收報6.94元,升0.58%。 農行(1288)創上市新高,見5.14元,收報5.09元,升0.59%。 工行(1398)收報5.64元,升0.18%。 郵儲行(1658)收報5.06元,無升跌。 交行(3328)創52周高,見7.27元,收報7.18元,跌0.28%。 招行(3968)收報49.35元,升0.1%。 中行(3988)收報4.68元,跌0.64%。 多間公司最快今日公布業績,績前表現如下,吉利(0175)創52周高,見19.66元,收報19.6元,升2.4%。 貝殼-W(2423)收報50.95元,跌4.14%。 中國黃金國際(2099)收報51.05元,跌1.73%。 正大企業國際(3839)收報1.62元,無升跌。 吉星新能源(3395)收報0.068元,無升跌。 LHN(1730)收報2.7元,無升跌。 敏華控股(1999)收報4.51元,升0.89%。 俄鋁(0486)收報4.15元,跌1.19%。 首程控股(0697)收報1.66元,跌3.49%。 南戈壁(1878)收報2.35元,跌1.67%。 中石化(0386)母公司出資12.32億港元增持3.02億股H股。收報4.09元,跌0.49%。 惠譽降萬科(2202)信貸評級一級至CCC+。萬科據報已償還年內唯一到期美元債,另獲大股東深鐵貸款最多15.5億人幣。收報5.51元,跌0.18%。 偉易達(0303):關稅下正加快中國以外生產,正與美國零售商討論分擔關稅成本。偉易達全年純利跌近6%末期息0.44美元, 擬分散生產地減關稅戰影響。收報52.3元,跌8.17%。 力寶(0226)系公司申報4844萬元增持金地商置至29.07%股權。收報0.46元,跌1.08%。 獅騰(2562)與江蘇蘇豪雲商達成策略合作。收報17.98元,跌1.96%。 時代中國(1233)清盤呈請聆訊延期至8月11日。收報0.225元,跌0.88%。 中國新消費(8275)擬在今年第三季在港開兩間「茶大椰」門店。收報0.185元,升0.54%。 破頂股表現 破頂股包括,騰訊音樂-SW(1698)創上市新高,見67.65元,收報66.95元,升8.86%;比亞迪(1211)創上市新高,見431.2元,收報429.2元,升3.52%;中國財險(2328)創上市新高,見15.44元,收報15.2元,跌0.65%;農行(1288)創上市新高,見5.14元,收報5.09元,升0.59%;比亞迪股份(1211)創上市新高,見431.2元,收報429.2元,升3.52%;農業銀行(1288)創上市新高,見5.14元,收報5.09元,升0.59%;晉景新能(1783)創上市新高,見9元,收報8.95元,升2.05%;巨子生物(2367)創上市新高,見85.35元,收報84.6元,升4%;聲通科技(2495)創上市新高,見525元,收報505元,升21.39%;卓越教育集團(3978)創上市新高,見5.94元,收報5.82元,升0.17%;中煙香港(6055)創上市新高,見35.75元,收報34.9元,升7.72%;榮利營造(9639)創上市新高,見1.25元,收報1.15元,跌4.96%;零跑汽車(9863)創上市新高,見67.45元,收報66.4元,升0.91%;泡泡瑪特(9992)創上市新高,見200.8元,收報199元,升2.74%;比亞迪股份-R(81211)創上市新高,見397.6元,收報396元,升3.77%;A中金港元(3071)創上市新高,見1120.45元,收報1120.45元,升0.09%;A南方美元(3096)創上市新高,見921.15元,收報921.05元,升0.1%;A博時港元(3152)創上市新高,見1097.05元,收報1097元,升0.01%;富邦滬深港高股息(3190)創上市新高,見14.2元,收報14.12元,跌0.21%;吉利(0175)創52周高,見19.66元,收報19.6元,升2.4%;中移動(0941)創52周高,見85.6元,收報85.4元,升0.47%;交行(3328)創52周高,見7.27元,收報7.18元,跌0.28%;四川成渝高速公路(0107)創52周高,見4.41元,收報4.36元,無升跌;吉利汽車(0175)創52周高,見19.66元,收報19.6元,升2.4%;利基控股(0240)創52周高,見1.16元,收報1.16元,升0.87%;北京控股(0392)創52周高,見32.7元,收報32.4元,跌0.31%;中國食品(0506)創52周高,見3.35元,收報3.24元,跌0.61%。 破頂指數成份股包括,騰訊音樂-SW(1698)創上市新高,見67.65元,收報66.95元,升8.86%;比亞迪(1211)創上市新高,見431.2元,收報429.2元,升3.52%;中國財險(2328)創上市新高,見15.44元,收報15.2元,跌0.65%;農行(1288)創上市新高,見5.14元,收報5.09元,升0.59%;吉利(0175)創52周高,見19.66元,收報19.6元,升2.4%;中移動(0941)創52周高,見85.6元,收報85.4元,升0.47%;交行(3328)創52周高,見7.27元,收報7.18元,跌0.28%。 破底股方面 8隻股份創上市新低,包括暢由聯盟(1039)低見0.045元,收報0.045元,跌10%;聯洋智能控股(1561)低見0.041元,收報0.041元,跌2.38%;中國金屬利用(1636)低見0.25元,收報0.26元,跌7.14%;譽燊豐控股(2132)低見0.084元,收報0.085元,跌1.16%;遠洋集團(3377)低見0.131元,收報0.133元,跌1.48%;易緯集團(3893)低見0.092元,收報0.105元,升5%;FI二華夏納一百(7522)低見0.688元,收報0.69元,跌0.58%;FI二南方納指(7568)低見4.514元,收報4.526元,跌0.75%。 18隻股份創52周低,其中十隻包括,天大藥業(0455)低見0.13元,收報0.138元,跌18.82%;港灣數字(0913)低見0.17元,收報0.17元,跌2.3%;MAYER HOLDINGS(1116)低見0.26元,收報0.265元,跌8.62%;中國創新投資(1217)低見0.01元,收報0.01元,無升跌;智中國際(6063)低見0.141元,收報0.155元,跌3.13%;財華社集團(8317)低見0.061元,收報0.062元,跌10.14%;利駿集團香港(8360)低見0.48元,收報0.49元,無升跌。 異動股 上升異動股,包括,優矩控股(1948)收報2.5元,升30.89%;萬星控股(8093)收報0.073元,升30.36%;中國碳中和(1372)創52周高,見1.04元,收報1元,升29.87%;建德國際控股(0865)創52周高,見0.04元,收報0.036元,升28.57%;樂華娛樂(2306)創52周高,見1.96元,收報1.9元,升25.83%;大中華控股(0021)收報0.159元,升25.2%;新都酒店(8315)收報0.179元,升22.6%;華和控股(9938)收報0.105元,升22.09%;大人國際(1957)收報0.305元,升22%;聲通科技(2495)創上市新高,見525元,收報505元,升21.39%;微盟集團(2013)收報2.06元,升20.47%。 下跌異動股,包括,海王英特龍(8329)收報0.19元,跌45.71%;時富投資(1049)收報0.73元,跌36.52%;中國置業(0736)收報0.1元,跌33.33%;麥迪森控股(8057)收報0.103元,跌23.7%;天大藥業(0455)見52周低0.13元,收報0.138元,跌18.82%;高雅光學(0907)收報0.2元,跌17.01%;慕詩國際(0130)收報0.13元,跌16.67%;精技集團(3302)收報0.105元,跌16%;傲迪瑪汽車(8418)收報0.46元,跌14.81%;中國唐商(0674)收報0.112元,跌13.85%。   其他報道 滬深三大指數半日向下 滬指失守3400點

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